GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THYM | cis | rs9902453 | 1 | rs9890205 | chr17:28382704 | EFCAB5 | chr17:28256874-28435469:+ | -0.31 | -4.25 | 5.04E-5 | Coffee consumption (cups per day) |
| THYM | cis | rs9902453 | 1 | rs9890886 | chr17:28391076 | EFCAB5 | chr17:28256874-28435469:+ | -0.31 | -4.25 | 5.04E-5 | Coffee consumption (cups per day) |
| THYM | cis | rs9902453 | 1 | rs9891871 | chr17:28370191 | EFCAB5 | chr17:28256874-28435469:+ | -0.31 | -4.25 | 5.04E-5 | Coffee consumption (cups per day) |
| THYM | cis | rs9894429 | 1 | rs9894429 | chr17:79596811 | TSPAN10 | chr17:79609349-79615778:+ | 0.63 | 6.54 | 3.14E-9 | Eye color traits |
| THYM | cis | rs9902453 | 1 | rs9896062 | chr17:28357047 | EFCAB5 | chr17:28256874-28435469:+ | -0.31 | -4.25 | 5.04E-5 | Coffee consumption (cups per day) |
| THYM | cis | rs7223966 | 1 | rs9899788 | chr17:61756384 | TCAM1P | chr17:61934376-61941738:+ | -0.54 | -4.47 | 2.2E-5 | Body mass index |
| THYM | cis | rs7223966 | 1 | rs9901112 | chr17:61730617 | TCAM1P | chr17:61934376-61941738:+ | -0.54 | -4.41 | 2.72E-5 | Body mass index |
| THYM | cis | rs7223966 | 1 | rs9901507 | chr17:61765524 | TCAM1P | chr17:61934376-61941738:+ | -0.54 | -4.47 | 2.2E-5 | Body mass index |
| THYM | cis | rs9902453 | 1 | rs9902453 | chr17:28349095 | EFCAB5 | chr17:28256874-28435469:+ | -0.31 | -4.26 | 4.84E-5 | Coffee consumption (cups per day) |
| THYM | cis | rs7223966 | 1 | rs9903897 | chr17:61716705 | TCAM1P | chr17:61934376-61941738:+ | -0.53 | -4.38 | 3.02E-5 | Body mass index |
| THYM | cis | rs7223966 | 1 | rs9903903 | chr17:61762044 | TCAM1P | chr17:61934376-61941738:+ | -0.54 | -4.47 | 2.2E-5 | Body mass index |
| THYM | cis | rs9902453 | 1 | rs9906340 | chr17:28398977 | EFCAB5 | chr17:28256874-28435469:+ | -0.36 | -4.27 | 4.71E-5 | Coffee consumption (cups per day) |
| THYM | cis | rs7223966 | 1 | rs9908044 | chr17:61747032 | TCAM1P | chr17:61934376-61941738:+ | -0.54 | -4.47 | 2.2E-5 | Body mass index |
| THYM | cis | rs7223966 | 1 | rs9909992 | chr17:61731931 | TCAM1P | chr17:61934376-61941738:+ | -0.54 | -4.41 | 2.72E-5 | Body mass index |
| THYM | cis | rs7223966 | 1 | rs9912201 | chr17:61763208 | TCAM1P | chr17:61934376-61941738:+ | -0.55 | -4.23 | 5.47E-5 | Body mass index |